Plasma is the liquid, golden part of blood — home to blood cells and carrier of the body's vital substances. In this article you will get to know it simply and completely.
Plasma is the light, liquid part of blood, making up about 55% of total blood volume . This amber-colored liquid carries red cells, white cells and platelets floating within it — like a sea on which ships sail.
If you pour blood into a test tube and let it settle, or spin it in a centrifuge , blood separates into two parts: the heavy cells (mostly red blood cells) settle at the bottom and the yellow liquid above them is the plasma.
Although plasma looks like a simple liquid, its composition is highly complex:
Most of plasma is water; the carrier that moves everything around the body.
Albumin, antibodies (immunoglobulins) and clotting proteins such as fibrinogen.
Electrolytes, hormones, vitamins, nutrients and waste compounds such as urea.
Plasma is not just a carrier fluid; it performs four vital tasks:
Delivers nutrients from food, hormones and dissolved oxygen to every cell of the body.
Collects metabolic waste from cells and carries it to the kidneys and liver for disposal.
Carries antibodies and complement proteins — the body's defensive shield against microbes.
Holds clotting proteins so bleeding stops when injury occurs.
Donated plasma is turned into several vital products in blood-processing laboratories, each treating specific diseases:
In plasma donation, known as plasmapheresis , the donor's blood enters a machine; plasma is separated and blood cells are returned to the donor's body. That is why the body recovers faster than from whole-blood donation.
Interestingly, people with blood type AB are the universal plasma donors; their plasma can be given to all blood types — the reverse of red cells, where type O negative is universal.
No. The body quickly replaces lost water and proteins, and since blood cells are returned, anemia does not occur. Blood transfusion centers run the necessary tests before donation.
Plasma keeps its clotting factors; serum is plasma from which fibrinogen and clotting factors have been removed — like the yellow liquid seen after blood clots in a lab.
Regular plasma is separated from whole blood, while in PRP (platelet-rich plasma) the plasma is drawn off together with concentrated platelets and used to speed tissue repair in cosmetic and orthopedic treatments.
The amber color comes from pigments such as bilirubin and liver enzymes. A sharp color change (dark or green) can indicate chemical changes and the bag is discarded.
Plasma — the yellow liquid making up about 55% of blood — is the invisible pillar of life: it delivers food and hormones, removes waste, grants immunity and stops bleeding. Every donated plasma bag can save the lives of burn, hemophilia and immune-deficiency patients — which is why plasma is also called liquid gold.
This content is for general information and is not a substitute for medical advice. For treatment decisions consult a physician or blood transfusion centers.
DarmanAra Holding began operating in 2021 with the goal of managing and supervising the production and collection of high-quality Iranian plasma.
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